Low-molecular-weight hyaluronic acid (<10 kDa) and collagen peptides (<1000 Da) are formulated for deep skin penetration, with narrow molecular weight distribution, high solubility in aqueous serum systems, and stable performance in cold-process manufacturing.
Low-molecular-weight hyaluronic acid and hydrolyzed collagen for deep skin delivery
Our serum-grade ingredients are produced using advanced enzymatic hydrolysis and precision fermentation, resulting in low-molecular-weight actives that can penetrate deeper into skin layers. With narrow molecular weight distributions and exceptional purity, our ingredients deliver maximum efficacy in concentrated formulations.
HA as low as 3kDa and collagen peptides <1000 Da for deep penetration
Preserved molecular structure ensures maximum biological activity
Excellent solubility in aqueous and hydro-alcoholic serum systems
Backed by penetration studies and efficacy clinical trials
High-purity active raw materials for facial serums, ampoules and intensive skincare treatment formulas
Ultra-low molecular weight marine collagen peptide with excellent transdermal absorption. Supports skin regeneration, improves fine lines, widely used in anti-aging essence and concentrated ampoule formulas.
Ideal for: Anti-age serum, repair ampoule, brightening essence
View DetailsMulti-specification hyaluronic acid raw material, provides instant deep hydration. Stabilizes aqueous serum formulations, suitable for hydrating, soothing and barrier-repair concentrated treatments.
Ideal for: Hydrating serum, sensitive skin repair essence, facial treatment fluid
View DetailsVegan plant-derived peptide, mild and non-irritating. Enhances skin surface protection, fits clean beauty, vegan essence and organic intensive skincare lines.
Ideal for: Vegan serum, natural soothing treatment, organic facial essence
View DetailsTechnical parameters for serum and treatment formulation development
| Ingredient | Recommended Dosage | pH Range | Phase | Compatibility |
|---|---|---|---|---|
| Low-MW HA (<10 kDa) | 0.1-1.0% w/w | pH 5.0-7.0 | Water phase (cold process) | Avoid cationic polymers; stable with most actives |
| Nano-Collagen Peptides | 0.5-3% w/w | pH 5.0-6.5 | Water phase (cold process) | Compatible with vitamins C/E, niacinamide, peptides |
| High-Purity HA | 0.05-0.5% w/w | pH 5.5-7.5 | Water phase (cold process) | Preservative-free compatible; low endotoxin |
Key manufacturing steps for serum and treatment formulations
Dissolve low-MW HA and nano-collagen peptides in chilled deionized water (15-25°C) under gentle stirring to prevent degradation. Allow full hydration for 30-60 min. Avoid temperatures above 40°C.
Add supplementary actives (vitamins, niacinamide, botanical extracts) at temperatures below 40°C. Add heat-sensitive ingredients last. Ensure uniform dispersion without air entrapment.
Pass formulation through 0.22 μm PES membrane filter for microbial control. For preservative-free serums, maintain aseptic conditions throughout. Test bioburden per USP <61>.
Fill under aseptic conditions into airless pump, dropper or ampoule containers. Use UV-protective or opaque packaging for light-sensitive actives. Recommended shelf life: 12-18 months.
International standards and certifications for global market access
EC 1223/2009 compliant; CPNP notification ready
21 CFR Part 700; INCI naming compliant
Good Manufacturing Practice for cosmetics
Halal certification for Muslim markets
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